Tucson, AZ -- (Sports Network) - Nic Grigsby ran for 135 yards and three touchdowns on 20 carries, as the Arizona Wildcats handled the Toledo Rockets, 41-16, in a non-conference clash in Tucson.

Willie Tuitama threw for 292 yards and two scores on 25-of-33 pass attempts for Arizona (2-0), while Mike Thomas pulled down nine balls for 138 yards and a touchdown.

For Toledo (0-1), Aaron Opelt hit on 21-of-31 throws for 170 yards and a score. His main outlet was Stephen Williams, who grabbed 12 passes for 67 yards and a touchdown.

With just under five minutes left to play in the opening quarter, Arizona took the lead behind a 20-yard field goal by Jason Bondzio.

Grigsby then rumbled seven yards for a score late in the period to give the Wildcats a 10-0 advantage.

Toledo finally got on the board in the second quarter, as Alex Steigewald connected on a 20-yard field goal.

The Wildcats, though, responded moments later courtesy of a Grigsby 27-yard touchdown run.

Just over two minutes later, Steigewald hit on a 35-yard field goal for Toledo.

Grigsby added a late 11-yard touchdown scamper to give the Wildcats a 24-6 lead at the half.

Bondzio opened the second half scoring with a 26-yard field goal just over five minutes into the third quarter.

Toledo countered with a 21-yard field goal from Steigewald.

The Wildcats made it a 34-9 game just five seconds into the final quarter, as Tuitama threw a seven-yard touchdown pass to Delashaun Dean.

It took the Rockets less than two minutes to counter behind a three-yard touchdown pass from Opelt to Williams.

Tuitama capped the game's scoring with a 12-yard touchdown pass to Thomas late in the fourth quarter.

The Wildcats racked up 452 yards of total offense in the game, while holding Toledo to just 244 yards.