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2008 East Carolina Pirates Schedule
| Date | Time (ET) | Opponent | Result | Record |
| 08/30/2008 | 12:00 PM | at Virginia Tech | ||
| 09/06/2008 | 04:30 PM | West Virginia | ||
| 09/13/2008 | 03:00 PM | at Tulane | ||
| 09/20/2008 | TBA | at NC State | ||
| 09/27/2008 | 03:30 PM | Houston | ||
| 10/11/2008 | TBA | at Virginia | ||
| 10/18/2008 | 12:00 PM | Memphis | ||
| 11/02/2008 | 08:00 PM | at U-C-F | ||
| 11/08/2008 | 03:30 PM | Marshall | ||
| 11/15/2008 | 03:00 PM | at Southern Miss | ||
| 11/22/2008 | 04:00 PM | at U-A-B | ||
| 11/28/2008 | 01:00 PM | Texas-El Paso |
