Media outlets reported the FBI said the operation was discovered last week when while warrants were being served on three Columbia men thought to be convicted felons in possession of guns and ammunition.
FBI Supervisory Special Agency Donald Wood said during the weapons searches, the dog fighting operation and dogs were discovered.
Brooks Barchee Gillie, Tony Shuler and Dequan Antonio Smith have been charged with weapons violations.
The dogs have been taken to an American Society for the Prevention of Cruelty to Animals temporary shelter. They will remain there until a court decides where the dogs should go.
It was not known if the men have attorneys yet.
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