Justin Brown scored 16 points, including three 3-pointers, and Laquincy Rideau added 11 points for South Florida (2-2).
Nathan Hoover had 11 points for the Terriers (2-4), who have now lost four consecutive games.
South Florida plays Loyola of Chicago on Monday. Wofford plays Maryland Eastern Shore on the road on Tuesday.
For more AP college basketball coverage: https://apnews.com/Collegebasketball and http://twitter.com/AP_Top25
Elements of this story were generated by Automated Insights, http://www.automatedinsights.com/ap, using data from STATS LLC, https://www.stats.com
Copyright 2019 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.