WYFF-TV reports the Greenville County Coroner's Office identified the victim as 67-year-old Janice Miller Frazer.
State troopers say the crash was reported about 10:15 p.m. Monday on Highway 25, about seven miles north of Travelers Rest.
Frazer was driving a 2013 Kia and was traveling south in the northbound lanes, when she hit a 2007 Toyota head-on. Frazer died at the scene.
The other driver, whose name was not released, was taken to Mission Hospital in Asheville. That driver's condition was not immediately available.
Information from: WYFF-TV, http://www.wyff4.com/index.html
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